TGFβ3: Transforming Growth Factor-beta-3

Description

BACKGROUND The Transforming Growth Factors (TGFs) are multifunctional peptides that regulate growth and differentiation in a variety of cells. Recent data suggest that individual TGF-β isoforms (TGFβ1, -β2 and β3) have overlapping, yet distinct biological actions and target cell specificities, both in developing and adult tissues. TGF-β3 is a new isoform that is presumed to play an important role in wound repair and scarring. TGF-β 3 is also thought to be involved in osteoblast proliferation, chemotaxis, and collagen synthesis.

Recombinant human/mouse TGFβ3 is a non-glycosylated, disulfide-linked homodimer. Each monomer is 112 amino acids, having a total molecular mass of 25.5 kDa.

Products are for research use only. They are not intended for human, animal, or diagnostic applications.

Details

Cat. No.:
RP1109AF
 
Alternative Name:
None
 
Source:
E. coli
 
Physical Appearance:
Sterile filtered clear solution.
 
Formulation:
Recombinant human/mouse TGF-β 3 is provided in a solution (0.25 mg/ml) that contains 10 mM acetic acid and 20% Ethanol.
 
Stability:
Stable at 4°C for 1 year from date of purchase.
 
Reconstitution:
Not applicable.
 
Protein Content and Purity determined by:
Quantitation against a known standard via reducing and non-reducing SDS-PAGE gels.
 
Endotoxin Level:
Endotoxin level, as measured by LAL analysis, is <1EU/ug.
 
Biological Activity:
The activity is determined by inhibition of IL-4-induced HT-2 cell proliferation.
 
AA Sequence:
MALDTNYCFR NLEENCCVRP LYIDFRQDLG WKWVHEPKGY YANFCSGPCP YLRSADTTHS TVLGLYNTLN PEASASPCCV PQDLEPLTIL YYVGRTPKVE QLSNMVVKSC KCS
 
Animal Component-Free
This product is produced with no animal derived raw products.

 

 

Products

Product Size CAT.# Price Quantity
Human TGF-b3, Animal-Free: Human TGF-β3, Animal-Free Size: 10 ug CAT.#: RP8007AF-10 Price: $213.00
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Human TGF-b3, Animal-Free: Human TGF-β3, Animal-Free Size: 100 ug CAT.#: RP8007AF-100 Price: $923.00
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Human TGF-b3, Animal-Free: Human TGF-β3, Animal-Free Size: 1000 ug CAT.#: RP8007AF-1000 Price: $7,577.00
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