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About

Company Description
Click Image to see Company Overview (Video) Since 1994, Cell Applications, Inc. has been a recognized global leader in isolation and purification of Primary Cells, and their culture in optimized, cell type-specific media. Early on, we recognized the demand for physiologically relevant, high quality primary cells, and now offer deep experience handling the notoriously sensitive and finicky cells.  CAI is built on strong foundations of high cell purity, quality control and characterization. With extensive hands-on experience, our highly trained PhD Scientists offer strong technical support. In addition, standardized, step-by-step instructions are provided, laboratory-tested and unique to each cell, tissue and species.
Our cell biology products and custom services support basic life science in the world's top universities and research institutes, as well as drug discovery and development in leading pharmaceutical, biotechnology, consumer health and cosmetic companies. To push the edges of scientific discovery, we launched our Center for Primary Cell Technology & Innovation in early 2016, encouraging lab researchers to work alongside our scientists at CAI on projects like tissue engineering, spheroid generation and protocol development.  Regular advancements are made in collaboration with academic investigators, industry experts and Scientific Advisors.  In February 2016, we announced a key strategic partnership with Cyfuse Biomedical K.K., in which primary cells are leveraged with 3D Cell Bioprinting.  Then in June, an alliance was formed with Induced Pluripotent Stem Cell innovator Stemonix, Inc.
CAI’s well-equipped primary cell toolbox includes stem cells, differentiation, spheroid generation, 3D Bioprinting, tissue engineering and 3D cell models.  Specialized media, culture reagents, growth factors, transfection reagents, antibodies, RNA and other supporting products extend and complement the applications available for these cells.  Scientists routinely cite CAI cells, media and cell biology products, including articles and patents for Nobel-awarded breakthroughs. Made using standard operating procedures, quality control, and extensive characterization, our manufacturing, packaging, management systems, standards and guidelines are approved to FDA 21 CFR Part 820 (cGMP). Now entering our third decade of business, we welcome the opportunity to energize your discoveries!
Primary Cells
Cell-based experiments play a key role in biomedical breakthroughs and depend on the establishment of healthy cell populations.  The cell type used for these experiments is critical.  Isolated directly from tissue, primary cells resemble normal physiology and lack modifications associated with immortalized, genetically-altered cell lines. For the typical lab, however, the successful isolation of healthy primary cells requires extensive training, substantial time, money and human resources.  Even then, protocols and results vary, and cells are subject to contamination.  Also, mass-produced, general-use culture media are not optimized for the unique requirements of individual primary cell types.
Primary cells are first carefully removed and released from tissue, and then established as a population in a controlled culture environment.  The primary cells in our comprehensive library are low passage and robust, with high viability, transfection efficiency and guaranteed doublings.  To maintain optimal cell health, behavior and performance, our media, reagents and conditions are painstakingly optimized for each cell type.  We can expand, freeze, document and test cells isolated from nearly any tissue or species.  Altogether, CAI offers many unique human and animal cell types, available in various sizes and packaging configurations.  These formats include freshly isolated, cultured, proliferating or cryopreserved cells.  Frozen vials, microwell plates, flasks or easy-to-use Total Kits provide further options.  We maintain multiple lots, with unique profiles of donor age, gender, ethnicity, disease status, and even medications taken.  Tissues and cells can also be isolated in matched sets from the same donor.
Quality
  • Low passage, robust, high viability & transfection efficiency, guaranteed doublings
  • Media and reagents optimized for each cell type
  • Published extensively, including Nobel-awarded breakthroughs. Isolated using standard operating procedures, quality control, and extensive characterization
  • Manufacturing, packaging, management systems, standards and guidelines approved to ISO 9001 and cGMP
Selection
  • Extensive array of human & animal cell types, in numerous ordering configurations
  • Freshly isolated, cultured, proliferating or cryopreserved cells, convenient sizes & formats
  • Frozen vials, microwell plates, flasks or easy-to-use Total Kits
  • Multiple lots, unique profiles of donor age, gender, ethnicity
  • Normal or diseased donors, matched sets from  same donor
Support
  • Into our third decade of expert isolation, purification, subculture and growth of primary cells, both standard and custom
  • Deep hands-on experience, step-by-step, laboratory-tested instructions, strong technical support
  • Direct sales, sound logistics and global distribution 

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