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Rat Schwann Cells: RSC

(Click to Enlarge) Rat Schwann Cells: RSC phase contrast image (Left) and RSC stained red for schwann cell marker S100β and nuclei counter-stained blue with DAPI (Right)
Instructions RSC
5 Important Cell Culture Rules
Cell Apps Flyer Nervous System
MSDS Cryopreserved Cells
Cell Apps Poster Primary Cells
Cell Applications Inc Brochure
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Rat Schwann Cells (RSC) are the principle glial cells in the peripheral nervous system, providing physical and chemical supports for neurons.  Myelinating Schwann cells surround neuronal cell bodies (sensory ganglia) and fibers (sensory and motor neurons) to form an insulating sheath. Periodic exposure of the axonal membrane to the extracellular space at the nodes of Raniver (myelin sheath gaps) allows rapid propagation of action potentials along the axon.  RSC are important for morphology, survival and growth of axons & neurons.  Studies also indicate Schwann cells promote neuronal restoration and experimental spinal cord regeneration.
The calcium binding protein S100β, a marker present in cultured Schwann cells, participates in paracrine mechanisms and neuronal maintenance.  S100β exerts neurotrophic effects to both peripheral sensory and motor neurons, and demonstrates experimental promise to repair, restore or treat nerve injuries and CNS lesions.
Characterization: Rat Schwann Cells from every lot stain Positive for S100β, attach & spread on tissue culture ware and proliferate in Rat Schwann Cell Growth Medium.
TissueNormal healthy adult rat peripheral nerves
QCNo bacteria, yeast, fungi, mycoplasma
CharacterPositive for S100β
BioassayAttach, spread, proliferate in Gr Med
Cryovial500,000 RSC (1st passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO
KitCryovial frozen RSC (R842-05a), Growth Medium (R825-500), Subcltr Rgnt Kit (090K)
ProliferatingShipped in Gr Med, 1st psg (flasks or plates)
DoublingsAt least 3
ApplicationsLaboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.

Products

Cryopreserved RSC

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Description
Size
Cat. #
Price
Cryopreserved RSC Frozen RSC (5x10^5) 1 Cryovial R842-05a $355.68

Cryopreserved RSC Total Kit

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Description
Size
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Cryopreserved RSC Total Kit 5x10^5 Cells, Medium & Subculture Reagents (See Details tab for specifics) 1 Kit R842K-05a $426.81

Proliferating RSC

Pricing
Description
Size
Cat. #
Price
Proliferating RSC Actively growing, dividing cells in medium T-25 Flask R843-25a $355.68
Proliferating RSC Actively growing, dividing cells in medium 6 Well R843-6Wa $462.38
Proliferating RSC Actively growing, dividing cells in medium T-75 Flask R843-75a $462.38
Proliferating RSC Actively growing, dividing cells in medium 96 Well R843-96Wa $533.51

Related Products

Rat Schwann Cell Basal Medium

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Description
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Rat Schwann Cell Basal Medium Basal medium (contains no growth supplement). Add GS before use. 500 ml R824-500 $46.13
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Rat Schwann Cell Growth Medium

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Description
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Rat Schwann Cell Growth Medium All-in-one ready-to-use media 500 ml R825-500 $148.63
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Rat Schwann Cell Growth Medium Kit

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Description
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Rat Schwann Cell Growth Medium Kit Basal medium & growth supplement sold together packaged separately Yields 500 ml R825K-500 $158.88
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Rat Schwann Cell Growth Supplement

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Description
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Weight
Rat Schwann Cell Growth Supplement Added to Basal Medium to create Growth Medium 50 ml R825-GS $128.13
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Extended Family Products

Anti-S100B

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Description
Size
Cat. #
Price
Anti-S100B Mouse S100B Antibody 100 ul CP10223 $333.13

Cell Freezing Medium

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Description
Size
Cat. #
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Cell Freezing Medium For general cryopreservation of most primary cells. Contains FBS & DMSO. 50 ml 040-50 $53.81

Cyto-X Colorimetric Cell Counting Reagent

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Description
Size
Cat. #
Price
Cyto-X Colorimetric Cell Counting Reagent 500 tests 1 Bottle 028-01 $138.84
Cyto-X Colorimetric Cell Counting Reagent 100 tests Sample 028-S $35.88

Subculture Reagent Kit

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Description
Size
Cat. #
Price
Subculture Reagent Kit 100 ml each of HBSS, Trypsin/EDTA & Trypsin Neutralizing Solution 1 Kit 090K $54.89