Familial Adenomatous Polyposis (FAP) is a genetic disorder caused by an inherited or spontaneous mutation. In classic FAP cases, polyps form in the colon and rectum as early as the teenage years. Most patients with Familial Adenomatous Polyposis eventually need surgery to remove the large intestine is surgically as a preventative measure. Subsequent monitoring and removal of spontaenous polyps in the duodenum is further required as part of treatment. If untreated, the large intestine polyps can lead to colorectal cancer later in life.
To better understand Familial Adenomatous Polyposis and disease treatment, Cell Applications offers researchers access to a first-of-kind biobank of Precancer Epithelial Cells. These epithelial cells were sampled from different sections of the FAP colon.
For your convenience, the Epithelial Cell Total Kit includes all the reagents you need for gastrointestinal epithelial cell culture. Along with a cryovial of 500,000 diseased epithelial cells, the Total Kit includes optimized cell culture medium, thawing medium, and coating solution. Cells can be cultured up to 7 days. Cells cannot be passaged and should be plated directly into the experimental system.
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|Tissue||Human colon of Familial Adenomatous Polyposis (FAP) donor.|
|QC||No bacteria, yeast, fungi, mycoplasma, virus.|
|Bioassay||Attach, spread, in Culture Medium.|
|Cryovial||500,000 HCnEpC-FAP in Freezing Medium.|
|Kit||Cryovial frozen HCnEpC-FAP (732Cn-FAP-05a), Culture Med (716DC-50), Coating Solution (025-05), Thawing Solution (716T-20).|
|Cultured||Shipped in flasks or plates in medium.|
|Doublings||Cells do not divide, and cannot be passaged. Cells can be cultured up to 7 days.|
|Applications||Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use.|
|Cryopreserved HCnEpC-FAP: Frozen HCnEpC-FAP (5x10^5) from ascending colon, 16 yr old male with Familial Adenomatous Polyposis.||Size: 1 Cryovial||CAT.#: 732Cn-FAP-05a-0030073||Price: $1,150.00|
|Cryopreserved HCnEpC-FAP: Frozen HCnEpC-FAP (5x10^5) colon at 35, 16 yr old male with Familial Adenomatous Polyposis.||Size: 1 Cryovial||CAT.#: 732Cn-FAP-05a-0030075||Price: $1,150.00|
|GI Epithelial Cell Defined Culture Medium: All-in-one medium, includes antibiotics. Store at -20C. Once thawed, store at 4C and use within 4 weeks.||Size: 50 ml||CAT.#: 716DC-50||Price: $55.00|
|GI Epithelial Cell Coating Solution: Coating solution for GI Epithelial Cells||Size: 5 ml||CAT.#: 025-05||Price: $16.00|
|GI Epithelial Cell Thawing Solution: Thawing solution for GI Epithelial Cells||Size: 20 ml||CAT.#: 716T-20||Price: $26.00|