BDNF is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer\'s and Huntington disease patients.2 BDNF may play a role in the regulation of stress response and in the biology of mood disorders.3 Multiple transcript variants encoding distinct isoforms have been described for this gene.
2. Ciammola, A. et al: Am. J. Med. Genet. Pt.B 144B:574-7, 2007
3. Duman, R.S. & Monteggia, L.M. : Biol. Psych. 59:1116-27, 2006
Target Protein Species:
31.2 pg/ml – 2000 pg/ml
No detectable cross-reactivity with other cytokines
Store at 4°C. Use within 6 months.
|Human BDNF ELISA Kit: Human Brain Derived Neurotrophic Factor ELISA Kit||Size: 96 Wells||CAT.#: CL0307||Price: $484.00|
Hu, J., L. Shen, R. Wang, Q, Wang, C. Zhang, J. Xi, S. Ma, J. Zhou, and H. Lu. 2012. Effects of Olig2-Overexpressing Neural Stem Cells and Myelin Basic Protein-Activated T Cells on Recovery from Spinal Cord Injury. Neurotherapeutics, 9:422-445.