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Rat Marrow Stromal Cells (RMSC) are isolated from rat bone marrow and are cryopreserved at second passage. RMSC can be cultured and propagated 10 population doublings. In addition to supporting hematopoietic cells1, marrow stromal cells can be induced to differentiate and express the traits of multiple cell lineages, including connective tissue (such as bone, cartilage, and fat)2,3,4,5 and neural cells6,7. The multipotent potential of RMSC in vitro provides new avenues for cell-based therapy, and studies have demonstrated the use of 3-D scaffolds for tissue engineering using RMSC8,9,10.
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Rochefort, GY et al., Stem Cells 24(10):2202 (2006).
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Yeon Lim, J et al., Exp Neurol. 199(2):416 (2006).
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Sergeeva, NS et al., Bull Exp Biol Med. 141(4):530 (2006).
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Backesjo, CM et al., J Bone Miner Res. 21(7):993 (2006).
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Want, Q et al., Biochem Biophys Res Commun. 347(1):117 (2006).
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Yang, LY et al., Biomed Environ Sci. 19(5):329 (2006).
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Tohill, M et al., Neurosci Lett. 362(3):200 (2004).
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Li, M et al., Conf Proc IEEE Eng Med Biol Soc 6(1):5858 (2005).
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Claase, MB et al., J Mater Sci Mater Med. (2007).
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Coleman, RM et al., Biomaterials. 28(12):2077 (2007).
Products are for research use only. They are not intended for human, animal, or diagnostic applications.
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Tissue:
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Rat bone marrow
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Cryopreserved ampoule:
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2nd passage, >500,000 cells in Rat Marrow Stromal Cell Basal Medium that contains 10% FBS and 10% DMSO.
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Kit contains:
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Ampoule of cryopreserved RMSC (R492-05a), 500 ml of Rat Marrow Stromal Cell Growth Medium (R419-500), and a Subculture Reagent Kit (090K).
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Proliferating Cells:
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Shipped in Rat Marrow Stromal Cell Growth Medium at 2nd passage in either flasks or multiwell dishes.
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Population doublings:
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Can be cultured at least 10 population doublings
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