Porcine Aortic Endothelial Cells (PAOEC) are derived from healthly, plaque free porcine aorta. PAOEC are cryopreserved at first passage and can be cultured and propagated at least 16 population doublings. Arterial endothelial cells play critical roles in cardiac homeostasis. Insults to the endothelial cells have been linked to a variety of vascular diseases. Porcine artery endothelial cells have been used as a viable alternative for the study of artery endothelial function and metabolism, such as atherosclerosis1, relaxing factor synthesis2, antioxidant enzyme activities3, etc. Co-culture of the artery endothelial cells with species-matched smooth muscle cells provides an ideal model for studying the interaction between these two cell types.
Ross, R.N., Nature 362:801 (1993).
Boulanger, C.M. et al, J. fo Vasc. Res. 34(3):175 (1997).
Bishop, C.T. et al, In Vitro Cell Devel. Biol. 21:229 (1985).
Animal tissues were USDA inspected.
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