Human Hepatic Stellate Cells: HHSC
Description
Hepatic Stellate Cells (HHSC) are one of the major cell type that reside between hepatocytes and blood vessels in the liver. HHSCs play an important role in liver homeostasis, maintenance and regeneration including retinol metabolism. Activation of stellate cells in disease state leads to liver fibrosis, hepatitis B & C, fatty liver disease, diabetes and other chronic diseases. Hepatic Stellate Cells are primary cells derived from human liver and cultured in optimized Hepatic Stellate Cells Growth Medium. Primary culture of Hepatic Stellate Cells is suitable for many cell-based assays including toxicity, drug screening and metabolism and is a valuable tool to study liver function, physiology and liver diseases
Characterization: Positive for α-smooth muscle actin and fibronectin by ICC staining.
Details
Tissue | Normal healthy human liver tissue | |
---|---|---|
QC | No bacteria, yeast, fungi, mycoplasma, virus | |
Bioassay | Attach, spread, proliferate in Growth Med | |
Cryovial | 500,000 HHSC (2nd passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO | |
Kit | Cryovial frozen HHSC (782-05f), Growth Medium (7117-500), Subcltr Rgnt Kit (090K) | |
Proliferating | Shipped in Gr Med, 2nd psg (flasks or plates) | |
Doublings | At least 15 | |
Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |
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