Human Hair Follicle Dermal Papilla Cells (HFDPC) are mesenchyme cells isolated from the hair papilla of normal human scalp hair follicles. They are cryopreserved at second passage, and can be cultured and propagated 6 population doublings. HFDPC can be used for the development and evaluation of hair growth products. Hair papilla, in the adult hair follicle, plays a crucial role in the dermal-epidermal interactions that control hair production and events of the hair growth cycle. It has been shown that cultured HFDPC can stimulate hair growth when implanted into an amputated follicle1. When used in a reconstitution model, HFDPC is an excellent tool for identifying cell populations within the hair follicle and studying the effects of specific gene products on hair follicle growth and development2.
Jahoda, C. et al, J. Invest. Dermatol. 101:584 (1993).
Weinberg, W. et al, J. Invest. Dermatol. 100: 229 (1993).
Each lot tested negative for HIV, Hepatitis B and Hepatitis C and negative for mycoplasma, bacteria, yeast, fungi.
Products are for research use only. They are not intended for human, animal, or diagnostic applications.