Previously, most research in adipocyte biology was conducted in mouse 3T3-L1 cell lines1,2,3. It was impossible to use human adipocytes because they die within 24 hours after isolation. To facilitate the study of human adipocyte biology, now we provide HAd (Human Adipocytes) which were differentiated from HPAd (Human Preadipocytes) through use of Adipocyte Differentiation Medium. Cells are shipped 10 to 14 days after initiating differentiation. Mature HAd are expected 15 days after induction of differentiation and should remain healthy and responsive for at least 2 weeks after complete differentiation to mature HAd. Adipose mass can be controlled by inhibition of HPAd differentiation and increase of lypolysis. HAd are ideal cellular models for drug discovery research in the area of obesity and diabetes.
Russel, T. R. et al, Proc. Natl. Acad. Sci. USA 73:4516 (1976)
Schmidt, W. et al, J. Biol. Chem. 265:15489 (1990)
Spiegelman, B. M. et al, Cell 24:503 (1981)
Each lot tested negative for HIV, Hepatitis B and Hepatitis C and negative for mycoplasma, bacteria, yeast, fungi.
Products are for research use only. They are not intended for human, animal, or diagnostic applications.