Human Bronchial Epithelial Cells, HBEpC, are derived from the surface epithelium of normal human bronchi. They are cryopreserved at first passage and can be cultured and propagated at least 16 population doublings. Airway epithelial cells are targets in asthma, viral infection, and fibrotic lung disease. These cells have been used to study the regulation of intracellular pH1, the stimulant effect of IL-1b on airway epithelial cell growth2, and the effect of human rhinovirus infection in terms of upregulation of ICAM-1 expression on epithelial cells3.
Poulsen, J.H. et al, J Physiol.-Abs. Vol. 432 (3) (1996).
- Murlas, C.G. et al, Lung 175: 117-126 (1997).
- Terajima, M. et al, Lung cellular and molec. physiology, 273 (4):749-759 (1997).
Characterization: Typical epithelial cell morphology.
Each lot tested negative for HIV, Hepatitis B and Hepatitis C and negative for mycoplasma, bacteria, yeast, fungi.
Products are for research use only. They are not intended for human, animal, or diagnostic applications.