Bovine Renal Artery Endothelial Cell (BRAEC) are derived from renal artery of USDA inspected cattle. They are cryopreserved at the second passage and can be propagated at least 10 doublings. Endothelial cell dysfunction is the primary cause of no reflow phenomenon in postischemic kidneys1. Low endothelial nitric oxide synthasae activity may contribute in hypertension2,3 in renal failure patients. BRAEC have been used as a cellular model for studying the pathogenesis of septic shock4.
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1. Brodsky, S.V. et al, Am. J. Physiol Renal Physiol. 282(6):F1140 (2002).
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2. Goonasekera, C.D. et al, Pediatr. Nephrol. 12(8):676 (1998).
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3. Xioa, S. et al, Acta Physiol. Scand. 168(1):175 (2000).
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4. Lama, S. et al, Am. J. Physiol. 261(4 pt 1):C634 (1991).
Products are for research use only. They are not intended for human, animal, or diagnostic applications.
Animal tissues were USDA inspected.
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