Human Skeletal Muscle Cells: HSkMC
Description
- Serve as a differentiated control in a study of developmental regulator genes in hESC
- Characterize statin-induced gene expression changes and demonstrate cytotoxic effect of statins in skeletal muscle cells
- Identify molecular mechanisms of mitochondrial myopathy and sideroblastic anemia resulting from a missense mutation in the PUS1 gene
- Investigate chemokine-like factor expression in the idiopathic inflammatory myopathies
- Demonstrate that fasting activates AceCS2 gene expression by inducing KLF15 transcription factor
- Characterize human FGFR3-positive sarcoma-initiating stem cells
- Identify trans-Golgi network proteins and Notch and Hedgehog pathways as putative targets for rhabdomyosarcoma therapy
- Show that riluzole muscle relaxant effects are mediated by inhibition of INa and stimulation of BKC-channel activity
- Develop nitric esters that combine the pharmacological functions of NO and muscle relaxation properties for treatment of muscular diseases
- Develop biodegradable polymer-based transgene delivery vectors for muscular dystrophy treatment
- Design optimal coating for orthopedic metallic implants
Details
Tissue | Normal healthy human limb skeletal muscle |
QC | No bacteria, yeast, fungi, mycoplasma, virus |
Character | Multinucleated myotubes form after culture in fusion medium |
Bioassay | Attach, spread, proliferate in Growth Med |
Cryovial | 500,000 HSkMC (2nd passage) frozen in Basal Medium w/ 10% FBS, 10% DMSO |
Kit | Cryovial frozen HSkMC (150-05), Growth Medium (151-500), Subcltr Rgnt Kit (090K) |
Proliferating | Shipped in Tsfr Med, psg 3, flasks or plates |
Doublings | At least 15 |
Applications | Laboratory research use only (RUO). Not for human, clinical, diagnostic or veterinary use. |