Because cell signaling pathway strength can vary among donors, researchers must set aside valuable resources in the screening of endothelial cells, skeletal muscle cells, and adipocytes for sensitivity to VEGF, Insulin, and other stimuli. Cell Applications Pre-Screened Cells take away the guess work so that your resources can be devoted directly to drug screening and drug validation experiments, and studies in angiogenesis, insulin signaling, and metabolic regulation. Our Pre-Screened Microvascular Endothelial Cells, Aortic Endothelial Cells, and Umbilical Vein Endothelial Cells, have been stimulated by VEGF, then assayed for phosphorylation and activation of the VEGFR2, MAP kinase, Akt, Tie2, Axl, eNOS, and Etk signaling pathways. Our Pre-Screened Skeletal Muscle Cells are stimulated with insulin and oligomycin, then verified for activation of Akt, MAPK, AMPK, and GSK cell signaling. Our Pre-Screened Pre-Adipocytes are differentiated into Adipocytes, and assayed for adipocyte and cell metabolic regulation markers such as PPAR, CEBP, Insulin Receptor, Adiponectin. Click on the cells below for more information on these time-saving cells.
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