| Cat.# |
CB0286
|
| Size |
70
µg / 200 ml |
| Isotype:
|
mouse
monoclonal IgG1
|
| Epitope: |
recombinant
HIV-1 p24 protein |
| Species: |
HIV-1 |
| Storage: |
-20°
|
| MW:
|
24
kDa
|
|
Application:
|
WB
|
| Dilution:
|
1:1000
|
|
Background:
The HIV-1 p24 protein is derived
from a precursor polyprotein
of HIV, p55 that is cleaved into shorter polypeptides namely p24 (core),
p17 (matrix) and p7/p9 (nucleocapsid) proteins. The p24 protein is
nonglycosylated and is of approximately 24 kDa size. The protein forms
the core of the virus and
encapsulates the viral genetic code1. p24 antigen plasma
level is a good survival and AIDS progress or death surrogate markers in
HIV infected patients2.
HIV-1 p24 monoclonal antibody provides an very useful tool for
detection of p24 proteins.
References:
1.
Freed,
E. O., Somat Cell Mol Genet 26:13, 2001.
2.
Schupbach,
J., Int Arch Allergy Immunol 132:196, 2003.
|
|
Detection
of HIV-1 p24 proteins in Western blot by
HIV-1 p24 (36C8) monoclonal antibody.
|
